Severe Anaemia as A Predictor of Mortality in Heart Failure Patients

Abstract

Introduction: Anaemia at the time of diagnosis of heart failure is said to be an independent factor for mortality during the following years. In this study, the effect of severe anaemia at the time of diagnosis, in the outcome of heart failure in the form of in hospital mortality is studied.

Methods: One hundred eighty-four heart failure patients admitted in Manamohan Cardiothoraccic. Vascular and Transplant Centre between September 2011 to March 2012, age above 15 years were enrolled in the study. Baseline investigations and hemoglobin was done and the patients were followed up till discharge or in hospital mortality.

Results: Among the 184 heart failure patients 115(62.5%) had anaemia. When evaluated in a bivariate model, the odds ratio of death for patients with mild anaemia compared with patients with no anaemia was 3.90.6-22.6, p value 0.124) for moderate anaemia 4.5 (0.9-23.07, p value 0.064) and for severe anaemia 46.06 (8.6-246.05, p value 1000), respectively. On multivariate analysis severe anaemia 919 (5.6-149762.9, p value 0.009) was still found to be a significant predictor of mortality

Conclusion: Severe anaemia at the time of diagnosis of heart failure is an independent predictor of in hospital mortality