Perioperative Outcomes following Surgery of Brain Tumors: Assessment and Analysis of Risk Factors

Authors

  • Prakash Kafle Nobel Institute of Neurosciences, Department of Neurosurgery, Nobel Medical College Teaching Hospital, Biratnagar, Nepal Author
  • Phelix Rufus Bangalore Baptist Hospital, Hebbal, Bangalore, Karnataka, India Author
  • Nabin Paudyal Nobel Institute of Neurosciences, Department of Neurosurgery, Nobel Medical College Teaching Hospital, Biratnagar, Nepal Author
  • Narendra P Joshi Nobel Institute of Neurosciences, Department of Neurosurgery, Nobel Medical College Teaching Hospital, Biratnagar, Nepal Author
  • Babita Khanal Department of Pediatric Medicine, Nobel Medical College Teaching Hospital, Biratnagar, Nepal Author
  • Edmond Jonathan Christian Medical College and Hospital, Vellore, Tamil Nadu, India Author
  • Binod R Bhandari Bir Hospital, Kathmandu, Nepal Author
  • Mohan R Sharma Department of Neurosurgery, Maharajgunj Medical Campus, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author

DOI:

https://doi.org/10.59779/jiomnepal.1263

Keywords:

Brain tumor, preoperative KPS (Karnofsky performance status score), preoperative mRS (Modified Rankin scale score)

Abstract

Introduction: Cranial neurosurgery carries significant morbidity and mortality. Hence it is imperative to combine the latest available technological equipment with surgeon’s experience to prevent or reduce perioperative complications. It is also equally important to have a preoperative general assessment of the patient with functional status in particular to predict postoperative outcomes.

Methods: This is a prospective study consisting of 122 patients selected over a period of 5 years (March 2017-March 2022). The patient database was retrieved from the medical record department, Nobel Institute of Neurosciences, Nobel Medical College Teaching Hospital, Biratnagar, Nepal and the approval of Institutional review committee was obtained. Age, gender, tumor related factors (site, extent and size), preoperative Glasgow Coma Scale (GCS) score, Karnofsky Performance Status (KPS) score and Modified Rankin scale (mRS) grade and their correlation with patient’s perioperative outcome were assessed.

Results: Significant correlation was found between preoperative KPS score, mRS grade and patient’s perioperative outcome (low KPS score <70 and high mRS grade was associated with adverse outcomes). There was no positive correlation between age, gender and tumor related factors with outcomes.

Conclusion: Low KPS score <70 and a high Modified Rankin scale score were associated with adverse perioperative outcomes in patient’s undergoing elective craniotomy for brain tumor surgery.

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Published

2023-08-31

How to Cite

Kafle, P., Rufus, P., Paudyal, N., Joshi, N. P., Khanal, B., Jonathan, E., Bhandari, B. R., & Sharma, M. R. (2023). Perioperative Outcomes following Surgery of Brain Tumors: Assessment and Analysis of Risk Factors. Journal of Institute of Medicine Nepal, 45(2), 31-36. https://doi.org/10.59779/jiomnepal.1263

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