Epithelioid sarcoma: A rare cause of non-healing ulcer

Abstract

Epithelioid sarcoma, first described by Enzinger in 1970, is a rare slow-growing soft tissue malignancy, associated with a high incidence of regional recurrence and distant metastases. It is characterized by a proliferation of epithelium-like cells and the absence of a granuloma-like pattern with positivity for vimentin, cytokeratin. The recommended treatment is a wide resection with adequate margins, lymph node dissection. We report a 37-year-old male with chronic, non-healing ulcer in lower leg of seven years duration who was treated conservatively leading to recurrence of the lesion with metastasis up to left inguinal region resulting lymphedema of the penis.