Carbon dioxide laser therapy of cervical intraepithelial neoplasia

Authors

  • Pramila Pradhan Author
  • J.D. Andrews Author

DOI:

https://doi.org/10.59779/jiomnepal.64

Abstract

We present a prospective study of cytology, colposcopy and histology reports of the first 70 women treated with CO2 laser for CIN lesions in East Surrey Hospital, Redhill (U.K) from 1st Sep 1984 to 30th July 1986.
Follow-up evaluation consisted mainly of cytology sampling and colposcopy if needed. Initial follow-up was at 6 weeks after laser therapy, then 3 monthly for the first year, 6th monthly interval for the second year, and yearly thereafter for the rest of life.
Out of 70, 68 patients were regularly seen at the gynaecological clinic. Two patients left the country to live aboard, and advice being given to follow the above schedule and to send us the copy of the smear reports (were reported Normal up to 2 years). Nine out of 70 patients (12.8%) demonstrated abnormal cytology indicating the presence of CIN following laser therapy. All these cases were recolposcoped and rebiopsied for accurate diagnosis. Two out of 20 patients CIN grade II recolposcoped (10%) demonstrated persistent disease following primary laser therapy. Seven out of 42 patients in CIN grade III (16.6%) demonstrated persistent disease. Over 97% of the patients were cytologically free of CIN at the end of the study.
CO2 laser is an effective form of treatment of CIN leisons. Failure rate was just under 3%. We recommend that any follow-up protocol should include 3 monthly interval for the first year, then 6 monthly interval for the 2nd year and then yearly thereafter for the rest of the life.

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Published

1999-06-30

How to Cite

Pradhan, P., & Andrews, J. (1999). Carbon dioxide laser therapy of cervical intraepithelial neoplasia. Journal of Institute of Medicine Nepal, 21(1 & 2). https://doi.org/10.59779/jiomnepal.64