Frequency of Bile Bacteria in Gallstone Disease

Abstract

Introduction: Gallstone disease is among the bread and butter surgery for most general surgeons but role of bacteria in its formation is still an enigma.

Methods: Bile was obtained during cholecystectomy from the patients admitted for uncomplicated cholecystectomy which was cultured in standard culture medium. Demographic profile and nature of stones obtained were also compared.

Results: This study involved micro biological analysis of bile obtained from 528 patients undergoing cholecystectomy without other complication for duration of one year in BP Koirala institute of health sciences, Dharan. Study showed that incidence biliary infection was 4.8% with commonest organism being E coli followed by K pneumonia. Among various types of stones pigment stone were mainly found to be associated with infection than other types of stones.

Conclusion: The study shows that though biliary infection in patients with gallstone disease is not uncommon but its exact role in the pathogenesis of gallstone disease is not elusive.