Antibacterial activities of locally used toothpastes against dental pathogens

Authors

  • K.B Tiwari Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • U.T. Shrestha Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • A. Acharya Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • B. Subedi Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • B. Paudyal Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • M. Jnawali Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • p. SAKYA Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • U. KC Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
  • V.P Agrawal Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal

DOI:

https://doi.org/10.59779/jiomnepal.344

Keywords:

Streptococcus, Triclosan, Zone-of-inhibition

Abstract

Background: Toothpastes need to contain various antimicrobial agents in order to reduce, control and prevent different kinds of dental diseases. Different brands have their own composition and concentration of ingredients for their efficacy. The consumers should aware about the facts associated with their health.

Methods: The bacterial pathogens were isolated and identified from various dental samples. Antibacterial activities of 11 different toothpastes available locally in markets were assessed against the isolates by standard agar well diffusion method.

Result: Monomicrobial infections were observed in all cases. The bacterial pathogens were found to be Streptococcus mutans, S. salivarius, S. sanguis, S. sobrinus and S. mitis. Of the assayed toothpastes- Colgate Total, Colgate, Anchor White and Pepsodont were found to be highly effective against the pathogens.

Conclusion: The result showed that the toothpastes containing Triclosan as a major chemical ingredient posses significant antibacterial activities.

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Published

2008-08-31

Issue

Vol. 30 No. 2 (2008): Journal of Institute of Medicine

Section

Original Articles

License

Copyright (c) 2008 Journal of Institute of Medicine Nepal

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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