Clinical Profile and Immediate Outcome of Children admitted in Pediatric Intensive Care Unit with the Diagnosis of Sepsis
DOI:
https://doi.org/10.59779/jiomnepal.1347Abstract
Background:
Sepsis is a significant cause of death in children. The mortality ranges from 5% to 35% from developed countries to developing countries. The information regarding predictive factors for mortality and morbidity are limited, especially in developing countries. So the aim of the study is to find out the clinical profile, immediate outcome and factors associated with poor outcome of the children with sepsis admitted in Kanti Children Hospital.
Methods
It is a retrospective study conducted at the Pediatric intensive care Unit (PICU) of Kanti children hospital Kathmandu. The records of patients diagnosed with sepsis with clinical and laboratory parameters aged more than 30days to 14 years admitted to PICU of Kanti children hospital Kathmandu from 13th April 2024 to 17th September 2024 were analyzed.
Results
The most common symptom of presentation was fever (94.4%). The mortality rate of of sepsis was 26.41%. The pedictors associated with poor outcome which are statistically significant are patient requiring dialysis (P=0.016), presence of CNS disease (0.001), patient on mechanical ventilation (p=0.00) and the use of ionotropic support (0.010) and raised D-dimer (p=0.036).
Conclusion
Fever was the most common symptom of sepsis with a mortality rate was 26.41%. The predictors of poor outcome are patient requiring dialysis, presence of CNS disease, patient on mechanical ventilation, the use of ionotropic support and raised D-dimer.
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