Microbiological Profile and Drug Sensitivity Pattern in Persistently Discharging Ears: A Tertiary Level Hospital Based Retrospective Study

Authors

  • Bigyan R Gyawali Department of ENT, Head and Neck Surgery, Maharajgunj Medical Campus, Ganesh Man Singh Memorial Academy of ENT, Head & Neck Studies, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author
  • Rabindra B Pradhanaga Department of ENT- Head & Neck Surgery, Maharajgunj Medical Campus, Ganesh Man Singh Memorial Academy of ENT - Head & Neck Studies, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author
  • Pabina Rayamjhi Department of ENT, Head and Neck Surgery, Maharajgunj Medical Campus, Ganesh Man Singh Memorial Academy of ENT, Head & Neck Studies, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author
  • Kripa Dongol Department of ENT- Head & Neck Surgery, Maharajgunj Medical Campus, Ganesh Man Singh Memorial Academy of ENT - Head & Neck Studies, Tribhuvan University Teaching Hospita, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author
  • Mudit Gupta Department of ENT, Head and Neck Surgery, Maharajgunj Medical Campus, Ganesh Man Singh Memorial Academy of ENT, Head & Neck Studies, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author
  • Lava Shrestha Department of Clinical Physiology, Maharajgunj Medical Campus, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author
  • Kunjan Acharya Department of ENT- Head & Neck Surgery, Maharajgunj Medical Campus, Ganesh Man Singh Memorial Academy of ENT - Head & Neck Studies, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal Author

DOI:

https://doi.org/10.59779/jiomnepal.1114

Keywords:

Drug sensitivity, ear discharge, microbiological, persistent

Abstract

Introduction: Antimicrobial resistance is an emerging issue resulting from the misuse of antibiotics in today’s world. As an effect of it, cases with persistent ear discharge not responding to the conventional oral antibiotics prescribed in ear pathologies are seen increasing in our day to-day practice. This study aims to review the microbiological growth and the pattern of their antibiotic sensitivity in this group of population.

Methods: This was a retrospective study which was conducted at the Department of ENT-HNS of Tribhuvan University Teaching Hospital. Record files of all cases who presented with persistently discharging ear for more than 2 weeks and not responding to oral antibiotics, between January 2017 to March 2020 were assessed. Cases of chronic otitis media (COM) squamous with persistent discharge were excluded as most of the times it is the disease process rather than type of organism which causes the persistence of ear discharge despite the use of antibiotics.

Results: COM mucosal and cavity infection following modified radical mastoidectomy (MRM) were the commonest pathologies. Pseudomonas aeruginosa (PA) and Coagulase negative Staphylococcus (CoNS) were the commonest bacterial isolates. Pseudomonas aeruginosa showed a good sensitivity to antibiotics like Tazobactam and Piperacillin and resistance to conventionally used antibiotics like Ciprofloxacin and Levofloxacin. Similarly, CoNS had good sensitivity to antibiotics like Oxacillin and Levofloxacin and resistance to conventionally used antibiotics like Amoxicillin.

Conclusion: COM mucosal and post MRM cavity infection are the commonest pathologies presenting with persistent ear discharge with PA and CoNS as the predominant isolates. Pseudomonas aeruginosa holds a good sensitivity to drugs like Tazobactam and Piperacillin; and CoNS to drugs like Oxacillin and Levofloxacin.

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Published

2020-08-31

How to Cite

Microbiological Profile and Drug Sensitivity Pattern in Persistently Discharging Ears: A Tertiary Level Hospital Based Retrospective Study. (2020). Journal of Institute of Medicine Nepal, 42(2), 64-68. https://doi.org/10.59779/jiomnepal.1114

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